تأثیر واکنشگر فنتون در اصلاح سطح آلیاژ حافظه‎دار نایتینول برای کاربردهای پزشکی

نوع مقاله : علمی و پژوهشی

نویسندگان

دانشگاه صنعتی سهند

چکیده

آلیاژ حافظه دار نایتینول در تهیه ایمپلنت‌ها و استنت‌های پزشکی بسیار پرکاربرد است. اکسیداسیون حرارتی و پوشش نیترید تیتانیوم از جمله عملیات اصلاح سطح متداول برای این آلیاژ هستند و در مقابل فرایند اکسیداسیون به کمک واکنشگر فنتون روشی جدید در اصلاح سطح آلیاژهای نایتینول برای کاربردهای پزشکی محسوب می‌شود. به منظور بررسی تاثیر این فرایند جدید، آزمایشاتی برای مشخصه یابی و مطالعه رفتار خوردگی و زیست سازگاری سطوح اکسیدی در محلول شبیه سازی مایعات بدن طراحی گردید. متغیرهای دما و زمان اکسیداسیون مورد مطالعه قرار گرفتند و در نهایت بر اساس نتایج بدست آمده شرایط بهینه دمایی و زمانی تعیین گردید. بر اساس این نتایج، انجام فرایند اکسیداسیـون فنتون در دمای 65 درجه سانتیگراد به مدت 24 ساعت، سطح عاری از ترک ایجـاد می‌کند که زیست سازگاری مطلوب و مقاومت به خوردگی بالایی فراهم می‌کند و می‌تواند به بهبود عملکرد آن در محیط بدن کمک کند.

کلیدواژه‌ها

عنوان مقاله [English]

Effects of Fenton's Reagent on Surface Modification of Nitinol Shape Memory Alloy for Biomedical Applications

نویسندگان [English]

  • Ramin Asghari
  • Jafar Khalil Allafi
Sahand University of Technology
چکیده [English]

Nitinol shame memory alloy is very useful in manufacturing of medical implants and stents. Thermal oxidation and TiN coating are of common Nitinol surface modification processes and in return Fenton's oxidation using Fenton reagent is a new approach in modifying the surface of Nitinol for medical applications. To study the effects of this novel process, experimental tests including oxide surface characterization, investigation of corrosion behavior and biocompatibility of the created oxide surfaces in simulated body fluids were performed. Parameters such as temperature and duration of oxidation process were studied. Based on the results, the optimized conditions considering temperature and process duration were determined. Accordingly, Fenton's oxidation process at 65 oC for 24 hours can create an oxide surface without any cracks which produces desirable biocompatibility and corrosion resistance and helps to improve its in vivo performance.

کلیدواژه‌ها [English]

  • Shape Memory Alloy
  • Fenton's Oxidation
  • In vitro
  • Corrosion behavior
  • Biocompatibility

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