Optimization of Process Parameters of PLGA/CS Nano-bio-camposite as Tissue Engineering Scaffold

Document Type : Original Articles

Authors

• Sedigheh Vaezifar ¹
• Elham Halvani-Anaraki ²

¹ Payame Noor University, I.R. Iran

² IsfahanUniversity of Technology

10.22067/ma.v0i29.52754

Abstract

Tissue engineering, as an interdisciplinary science, is culturing cell body or stem cells outside the body and depositing grown and differentiated cell complex on substrate biomaterials into a patient's body. PLGA and chitosan are commonly used for tissue engineering applications, respectively as synthetic and natural polymers. In this study, nano-biocomposite scaffold of tissue engineering was prepared by electrospinning/electrospraying method. Nanofibers with random and aligned arrangement were prepared. The average particle size and fiber diameter was measured using Image J analysis software.

Keywords

• Electrospraying
• Electrospinning
• PLGA
• scaffold
• Chitosan Nanoparticles
• tissue engineering

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