Preparation of a Bilayer Coating of nHydroxyapatite/Poly(lactic-co-glycolic)acid on Mg and Investigation of Corrosion Properties and Biocompatibility

Articles in Press

Document Type : Original Articles

Authors

• Neda Aboudzadeh ¹
• Mina Mohamadizadeh ²
• Alireza Khavandi ³
• alireza eivani ³

¹ Department of Materials Science and Engineering, Iran University of Science and Technology (IUST), Tehran, Iran

² Ms. of Metallurgy & Materials Engineering Department, Iran University of Science and Technology, Tehran, Iran

³ Metallurgy & Materials Engineering Department, Iran University of Science and Technology, Tehran, Iran

10.22067/jmme.2024.83920.1121

Abstract

Abstract:

In this study, intending to control the corrosion of magnesium and its clinical application, a double-layer coating of Hydroxyapatite- Poly lactic-co-glycolic acid was applied on Mg by means of the electrodeposition and the dip method, respectively. X-ray diffraction (XRD) and scanning electron microscopy (SEM) are used to characterize the phase and morphology of the coatings. The results show a homogeneous coating with a thickness of 20-30 µm. Potentiodynamic polarization of the samples revealed that the double-layer coating exhibited a significant increase in corrosion potential, ranging from -1.82 to -1.4 V, and a decrease in corrosion current, ranging from 2.3 to 0.37 µA/cm2. Moreover, the MTT assay of the samples revealed that the amount of cell proliferation in the vicinity of the 48-hour extract of magnesium samples with double-layer coating had increased, indicating a decrease in the amount of ions released from the surface of magnesium by applying this coating.

Keywords

• Magnesium
• Hydroxyapatite
• Poly lactic-co-glycolic acid
• Double-layer coating
• Corrosion
• Biocompatibility

Main Subjects

• Biomaterials

---