Metal-Phenolic Networks as Antimicrobial and Anticancer Biointerfaces in Bio-Medical Applications

Document Type : Original Articles

Authors

Bioceramic and Implant Specialized Laboratory, Department of Life Science Engineering, Collage of Interdisciplinary Science and Technology, University of Tehran, Tehran, Iran

Abstract

Metal-phenolic networks are an emerging organic-inorganic hybrid network system that has been gradually developed in recent years through the coordination between metal ions and organic ligands containing phenolic groups, such as gallol or catechol. These networks exhibit exceptional multifunctional properties, specifically anti-inflammatory, antioxidant, and antibacterial functions. These materials greatly change the surface characteristics, resulting in improved performance in areas such as anti-corrosion, hydrophobicity, biocompatibility, and binding of specific molecule on various surfaces, including metals, oxides, polymers and biological materials. Furthermore, phenolic metal networks have attracted considerable attention in the field of infection prevention and advanced cancer therapies due to their easy synthesis process, remarkable biocompatibility, and outstanding antimicrobial properties facilitated by polyphenols and metal ions. The aim of this article is to provide an overview of the recent biomedical applications of phenolic metal networks in different structures, with a particular focus on their inherent characteristics, including novel antimicrobial and anticancer properties.

Keywords

Main Subjects


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