نوع مقاله : علمی و پژوهشی
عنوان مقاله English
نویسندگان English
The rapid spread of bacterial infections and the increasing prevalence of antimicrobial resistance have intensified the demand for the development of novel, safe, and efficient antibacterial materials. In this study, ternary ZnO/CuO/Clay nanocomposites were synthesized via solution combustion synthesis using glycine as a green fuel, and the effects of different phase ratios and clay contents on their structural characteristics and antibacterial performance were systematically investigated. Thermodynamic analysis revealed that the incorporation of kaolin reduced the adiabatic reaction temperature, thereby suppressing excessive particle growth and promoting the formation of finer nanoparticles with enhanced porosity. FE-SEM and EDS mapping analyses confirmed the uniform distribution of spherical ZnO and CuO nanoparticles on the surface and within the interlayers of kaolin, leading to the formation of stable heterojunction structures. BET results demonstrated the presence of mesoporous structures (3–5 nm) and a significant increase in specific surface area, particularly in samples containing 25% clay. Antibacterial evaluations against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus indicated superior performance for nanocomposites with 25% clay and higher ZnO and CuO contents, achieving 100% bacterial growth inhibition even at low concentrations. Mechanistic investigations suggested that mechanical disruption of the bacterial cell membrane, reactive oxygen species generation, and metal ion release are the dominant antibacterial pathways. Overall, the ZnO/CuO/Clay nanocomposites synthesized via solution combustion synthesis exhibit multifunctional and environmentally friendly characteristics, highlighting their strong potential for antibacterial and biomedical applications.
کلیدواژهها English
